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Nanomedicine, which involves the application of nanotechnology in medical treatments and diagnostics, holds immense promise for revolutionizing healthcare. It enables the delivery of drugs, the repair of tissues, and the targeting of diseases with unprecedented precision. However, its development also brings substantial challenges, particularly in risk assessment and predictive toxicology. Key issues include managing the unique biocompatibility and toxicity risks of nanoparticles, which can behave unpredictably in biological systems due to their size, shape, and surface properties. Effective risk assessment in nanomedicine requires tailored approaches to characterize and predict nanoparticle behavior, as traditional methods often fall short. Predictive toxicology, which combines in vitro testing, computational modeling, and high-throughput screening, is essential to foresee potential toxic effects and improve safety. As nanomedicine evolves, developing precise regulatory frameworks and public trust will be crucial for its responsible advancement in medical practice. The current presentation is centered on different challenges and risk assessment associated with nanomedicine followed by its predictive toxicology.
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